A. Historically the aging theory: This question plagued humanity since ancient times is a mystery. The history of the doctrine of aging a lot, but basically grouped into two major categories of the understanding of the mutually exclusive, that one is that aging is inherent in the human body, and over time the inevitable result of the degradation process ~ the natural evolution of doctrine; the other is that aging is the body of structural damage leading to tissue breakdown of the results of ~ unnatural evolution theory. With the rapid development of science and technology, people continued to deepen the study of aging, and often produce a new understanding of the old theories have been denied, but so far, the mechanism of aging is still not very clear. In general, aging is the body’s own intrinsic factors and environmental factors affecting the result of both. Obviously, as a life, is bound to its formation, growth, aging, dying process, not always exist; the same time, a life can not be divorced from the environment and independent existence of external factors, then the external factors can not be produced without their various the impact of various kinds. B. modern doctrine Currently, the major theories of aging research and theory are: the natural evolution, said: analysis of different nationalities, different ages of human life process of drawing out the curve of human life and found that different ethnic and age, human life curve is basically the same, that is the great difference in the objective conditions do not affect the basic form of life curve. Medical technology to improve people’s average life expectancy has markedly improved, but the impact of the highest life expectancy do not do so, indicating that the maximum human life is “natural” in. Genetic approach from animal life, human and animal cells in vitro results also shows that the phenomenon of the same species (kind) Animals (cell) and the difference in life expectancy between groups was not obvious, indicating that genetic factors are the main factors that determine life . Genetic mechanisms: In the natural evolution of that study, the most important elements is the genetic mechanism of aging research. One theory is that human development and aging is to have their own “password”. This password is dominated by natural selection, the decision is that the process of human evolution gradually formed. For an individual person, he (she) is born, the password has already decided his life, like a computer program, as has long been a good preparation for life processes to control their life. The password exists in the genes. In addition, the gene duplication theory and gene repair theory, have emphasized the human genes to their own circumstances and ability of the determinants of human life. In recent years, further development of the doctrine of apoptosis. Non-natural evolution, said: important non-genetic factors are the following saying: protein synthesis error doctrine: that the human body protein synthesis errors are very common phenomenon. However, if the transmission of genetic information that has occurred error enzymes will enable the enzyme activity decreased, resulting in a large number of errors in protein accumulation and loss of function in normal cell death, eventually leading to aging. Cell mutation theory: that the human cells and reproductive cells, can be a spontaneous mutation, mutant cells accumulated to a certain number, they will lead to dysfunction of the organization, eventually leading to aging. Which lead to mutations on a variety of substances, ionizing radiation and other study has confirmed the mutation and age-related. Immune theory: that aging and physical decline in immune function and immune system damage related to the body. Free radical theory: free radical reactions in normal physiological processes of cells is quite common, such as abnormal or uncontrolled free radical reactions would be damage to cell function. Such as “senile plaques” that is, protein and lipid free radical reaction products can not be broken down and clear the accumulation in the cells caused by. In addition, cross-linked macromolecules that metabolite accumulation that endocrine disorder that, and so forth. In general, it should be recognized that no single theory or theories alone can explain all of the aging phenomenon, aging is the result of many factors.